BDBM50170884 CHEMBL3805495
SMILES COc1ccc(CCNCC(N)P(O)(=O)CC(Cc2ccccc2)C(O)=O)cc1
InChI Key InChIKey=XGTZMRSSJSALMZ-UHFFFAOYSA-N
Data 5 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50170884
Affinity DataKi: 78nMAssay Description:Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...More data for this Ligand-Target Pair
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))
Wroclaw University Of Technology
Curated by ChEMBL
Wroclaw University Of Technology
Curated by ChEMBL
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of human ERAP2 preincubated for 30 to 60 mins followed by addition of Arg-AMC as substrate measured for 15 mins by spectrofluorimetric met...More data for this Ligand-Target Pair
Affinity DataKi: 1.48E+3nMAssay Description:Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
TargetCytosol aminopeptidase [33-68,L62W](Sus scrofa (Pig))
Wroclaw University Of Technology
Curated by ChEMBL
Wroclaw University Of Technology
Curated by ChEMBL
Affinity DataKi: 2.11E+4nMAssay Description:Inhibition of porcine kidney leucine aminopeptidase M17 using Leu-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition meas...More data for this Ligand-Target Pair
TargetEndoplasmic reticulum aminopeptidase 1(Homo sapiens (Human))
Wroclaw University Of Technology
Curated by ChEMBL
Wroclaw University Of Technology
Curated by ChEMBL
Affinity DataKi: >2.50E+5nMAssay Description:Inhibition of human ERAP1 preincubated for 30 to 60 mins followed by addition of Leu-AMC as substrate measured for 15 mins by spectrofluorimetric met...More data for this Ligand-Target Pair