BDBM50171264 CHEMBL197646::US11427604, Compound (I-43)::US11597738, Example 1::[2-(4-Fluoro-1H-indol-3-yl)-ethyl]-dimethyl-amine
SMILES CN(C)CCc1c[nH]c2cccc(F)c12
InChI Key InChIKey=ISJZKVWGUWBUFG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50171264
Affinity DataKi: 8.39nMAssay Description:Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]-LSD as radioligand with the compound (10 uM) dissolved in DMSOMore data for this Ligand-Target Pair
Affinity DataKi: 82nMAssay Description:Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...More data for this Ligand-Target Pair
Affinity DataKi: 84nMAssay Description:Inhibition constant against human 5-hydroxytryptamine 2C receptor [VGI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...More data for this Ligand-Target Pair
Affinity DataKi: 335nMAssay Description:Inhibition constant against human 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSOMore data for this Ligand-Target Pair
Affinity DataKi: 359nMAssay Description:Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand with the compound (10 uM) dissolved in DMSOMore data for this Ligand-Target Pair
Affinity DataKi: 1.01E+3nMAssay Description:Inhibition constant against rat 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSOMore data for this Ligand-Target Pair
Affinity DataIC50: <500nMAssay Description:Table 2: i. Prepare the assay buffer following the table below;Reagent ConcentrationTris 50 mMCaCl2 4 mMBSA 0.1% (w/v)Adjust pH to 7.4 followe...More data for this Ligand-Target Pair
Affinity DataEC50: 1.18E+3nMAssay Description:Effective concentration required for accumulation of [3H]-inositol phosphate in cells transiently expressing human 5-hydroxytryptamine 2B receptor de...More data for this Ligand-Target Pair
Affinity DataEC50: 949nMAssay Description:Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2A receptor determi...More data for this Ligand-Target Pair
Affinity DataEC50: 99nMAssay Description:Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2C receptor determi...More data for this Ligand-Target Pair