BDBM50171289 Benzenemethanesulfonyl fluoride::CHEMBL190503::PMSF::Phenylmethanesulfonyl fluoride::alpha-toluenesulfonyl fluoride::alpha-toluenesulphonyl fluoride::phenylmethylsulfonyl fluoride

SMILES FS(=O)(=O)Cc1ccccc1

InChI Key InChIKey=YBYRMVIVWMBXKQ-UHFFFAOYSA-N

Data  1 KI  6 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50171289   

TargetTrypsin(Homo sapiens (Human))TBA
LigandPNGBDBM50171289(Benzenemethanesulfonyl fluoride | CHEMBL190503 | P...)
Affinity DataKi:  1.00E+4nMAssay Description:Competitive inhibition of trypsin (unknown origin) using N-succinyl-phenylalanine-p-nitroanilide as substrate incubated for 20 mins prior to substrat...More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

Curated by ChEMBL
LigandPNGBDBM50171289(Benzenemethanesulfonyl fluoride | CHEMBL190503 | P...)
Affinity DataIC50:  9.52E+4nMAssay Description:Inhibition of human neutrophil elastase after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Chang Gung University

Curated by ChEMBL
LigandPNGBDBM50171289(Benzenemethanesulfonyl fluoride | CHEMBL190503 | P...)
Affinity DataIC50:  5.22E+4nMAssay Description:Inhibition of human leukocyte elastase after 2 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50171289(Benzenemethanesulfonyl fluoride | CHEMBL190503 | P...)
Affinity DataIC50:  833nMAssay Description:Inhibition of rat histidine tagged FAAH expressed in Escherichia coli by coumarin ester substrate fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))TBA
LigandPNGBDBM50171289(Benzenemethanesulfonyl fluoride | CHEMBL190503 | P...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of trypsin (unknown origin) using BApNA as substrate incubated for 15 min prior to substrate addition measured after 30 min by UV/VIS spec...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMyeloblastin(Homo sapiens (Human))
University Of Bergen

Curated by ChEMBL
LigandPNGBDBM50171289(Benzenemethanesulfonyl fluoride | CHEMBL190503 | P...)
Affinity DataIC50:  1.92E+4nMAssay Description:Inhibition of human PR3 using D-DY-FRET as substrate after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50171289(Benzenemethanesulfonyl fluoride | CHEMBL190503 | P...)
Affinity DataIC50:  1.30E+4nMAssay Description:Irreversible inhibition of fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed