BDBM50171429 2-[5-(3-Bromo-furan-2-yl)-[1,2,4]oxadiazol-3-yl]-5-trifluoromethyl-pyridine::CHEMBL363147

SMILES FC(F)(F)c1ccc(nc1)-c1noc(n1)-c1occc1Br

InChI Key InChIKey=SYMWZIQCLDZKKV-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50171429   

TargetCaspase-3(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171429(2-[5-(3-Bromo-furan-2-yl)-[1,2,4]oxadiazol-3-yl]-5...)
Affinity DataEC50:  700nMAssay Description:Caspase-3 activation activity tested in DLD1 colon cells done for 24 or 48 h at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171429(2-[5-(3-Bromo-furan-2-yl)-[1,2,4]oxadiazol-3-yl]-5...)
Affinity DataEC50: >1.00E+4nMAssay Description:Caspase-3 activation activity tested in H1299 lung cancer cells done for 24 or 48 h at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50171429(2-[5-(3-Bromo-furan-2-yl)-[1,2,4]oxadiazol-3-yl]-5...)
Affinity DataEC50:  610nMAssay Description:Caspase-3 activation activity tested in T47D breast cells done for 24 or 48 h at 37 degree CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed