BDBM50171516 CHEMBL363815::N-[4-(4,5-Dichloro-2-fluoro-phenylamino)-quinazolin-6-yl]-acrylamide

SMILES Fc1cc(Cl)c(Cl)cc1Nc1ncnc2ccc(NC(=O)C=C)cc12

InChI Key InChIKey=BYJCHKAVUQQEQZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50171516   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171516(CHEMBL363815 | N-[4-(4,5-Dichloro-2-fluoro-phenyla...)
Affinity DataIC50:  20nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 6.7-20 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171516(CHEMBL363815 | N-[4-(4,5-Dichloro-2-fluoro-phenyla...)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171516(CHEMBL363815 | N-[4-(4,5-Dichloro-2-fluoro-phenyla...)
Affinity DataIC50:  20nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 6.7-20 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed