BDBM50171516 CHEMBL363815::N-[4-(4,5-Dichloro-2-fluoro-phenylamino)-quinazolin-6-yl]-acrylamide
SMILES Fc1cc(Cl)c(Cl)cc1Nc1ncnc2ccc(NC(=O)C=C)cc12
InChI Key InChIKey=BYJCHKAVUQQEQZ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50171516
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University
Curated by ChEMBL
Hadassah Hebrew University
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 6.7-20 nMMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University
Curated by ChEMBL
Hadassah Hebrew University
Curated by ChEMBL
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University
Curated by ChEMBL
Hadassah Hebrew University
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 6.7-20 nMMore data for this Ligand-Target Pair