BDBM50171518 CHEMBL193159::N-[4-(3-Bromo-phenylamino)-quinazolin-6-yl]-2-chloro-acetamide

SMILES ClCC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1

InChI Key InChIKey=PCOWWMQRUYKPLC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50171518   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171518(CHEMBL193159 | N-[4-(3-Bromo-phenylamino)-quinazol...)
Affinity DataIC50:  32nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171518(CHEMBL193159 | N-[4-(3-Bromo-phenylamino)-quinazol...)
Affinity DataIC50: <5nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171518(CHEMBL193159 | N-[4-(3-Bromo-phenylamino)-quinazol...)
Affinity DataIC50:  10nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed