BDBM50171523 (4,5-Dichloro-2-fluoro-phenyl)-(6,7-dimethoxy-quinazolin-4-yl)-amine::CHEMBL437879

SMILES COc1cc2ncnc(Nc3cc(Cl)c(Cl)cc3F)c2cc1OC

InChI Key InChIKey=AWSNTTSKWKZQQT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50171523   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171523((4,5-Dichloro-2-fluoro-phenyl)-(6,7-dimethoxy-quin...)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171523((4,5-Dichloro-2-fluoro-phenyl)-(6,7-dimethoxy-quin...)
Affinity DataIC50:  5nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 3-5 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed