BDBM50171524 (E)-4-Dimethylamino-but-2-enoic acid [4-(3-iodo-phenylamino)-quinazolin-6-yl]-amide::CHEMBL189779

SMILES CN(C)C\C=C\C(=O)Nc1ccc2ncnc(Nc3cccc(I)c3)c2c1

InChI Key InChIKey=MCFYGOURGHBNOM-QPJJXVBHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50171524   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171524((E)-4-Dimethylamino-but-2-enoic acid [4-(3-iodo-ph...)
Affinity DataIC50: <5nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171524((E)-4-Dimethylamino-but-2-enoic acid [4-(3-iodo-ph...)
Affinity DataIC50:  0.940nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171524((E)-4-Dimethylamino-but-2-enoic acid [4-(3-iodo-ph...)
Affinity DataIC50: <5nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed