BDBM50172028 2-Hydroxy-4-methyl-4-phenyl-2-trifluoromethyl-pentanoic acid (1-oxo-1,3-dihydro-isobenzofuran-5-yl)-amide::CHEMBL196067

SMILES CC(C)(CC(O)(C(=O)Nc1ccc2C(=O)OCc2c1)C(F)(F)F)c1ccccc1

InChI Key InChIKey=WJEDKJKCQOZDNI-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50172028   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50172028(2-Hydroxy-4-methyl-4-phenyl-2-trifluoromethyl-pent...)
Affinity DataIC50:  79nMAssay Description:Binding affinity towards glucocorticoid receptor using fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50172028(2-Hydroxy-4-methyl-4-phenyl-2-trifluoromethyl-pent...)
Affinity DataIC50:  215nMAssay Description:Binding affinity towards mineralocorticoid receptor using fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50172028(2-Hydroxy-4-methyl-4-phenyl-2-trifluoromethyl-pent...)
Affinity DataEC50:  150nMAssay Description:Effective concentration against inhibition of Dexamethasone induced glucocorticoid receptor transactivation of mouse mammary tumor virus luciferase g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50172028(2-Hydroxy-4-methyl-4-phenyl-2-trifluoromethyl-pent...)
Affinity DataIC50:  36nMAssay Description:Binding affinity towards progesterone receptor using fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed