BDBM50172725 CHEMBL3809706

SMILES Cl.Cl.NCCCn1c2-c3ccccc3C(=O)c2c2ncccc2c1=O

InChI Key InChIKey=CBNFOAZZSUQBNF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172725   

TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50172725(CHEMBL3809706)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using single stranded 5'-[32P]-labeled DNA containing 3'-phosphotyrosine as substrate after 15 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50172725(CHEMBL3809706)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant TDP2 using 19-mer single stranded DNA containing 5'-phosphotyrosine as substrate after 15 mins by PAGEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed