BDBM50173355 1-(4-Methoxy-phenyl)-3-(3-trifluoromethyl-phenoxy)-1H-indole-2-carboxylic acid::CHEMBL198605

SMILES COc1ccc(cc1)-n1c(C(O)=O)c(Oc2cccc(c2)C(F)(F)F)c2ccccc12

InChI Key InChIKey=KYUONBXQBMWVRC-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173355   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173355(1-(4-Methoxy-phenyl)-3-(3-trifluoromethyl-phenoxy)...)
Affinity DataIC50:  115nMAssay Description:Inhibitory concentration against human peroxisome proliferator activated receptor gamma in SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173355(1-(4-Methoxy-phenyl)-3-(3-trifluoromethyl-phenoxy)...)
Affinity DataEC50:  334nMAssay Description:Effective agonist concentration for human PPAR gamma Gal4 construct in transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50173355(1-(4-Methoxy-phenyl)-3-(3-trifluoromethyl-phenoxy)...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory concentration against human peroxisome proliferator activated receptor alpha in SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed