BDBM50173705 (-)3-((1R,2R)-2-Dimethylaminomethyl-cyclopropyl)-1H-indole-5-carbonitrile::CHEMBL195774

SMILES CN(C)C[C@@H]1C[C@H]1c1c[nH]c2ccc(cc12)C#N

InChI Key InChIKey=DEMWBYUAYXJYOC-NWDGAFQWSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173705   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50173705((-)3-((1R,2R)-2-Dimethylaminomethyl-cyclopropyl)-1...)
Affinity DataKi:  8.90nMAssay Description:Binding inhibition towards human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50173705((-)3-((1R,2R)-2-Dimethylaminomethyl-cyclopropyl)-1...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed