BDBM50173708 CHEMBL198298::N,N-dimethyl-3-phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-amine

SMILES CN(C)CCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1

InChI Key InChIKey=QUFZVVNFYXEIAK-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173708   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50173708(CHEMBL198298 | N,N-dimethyl-3-phenyl-3-(4-(trifluo...)
Affinity DataKi:  7.70nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50173708(CHEMBL198298 | N,N-dimethyl-3-phenyl-3-(4-(trifluo...)
Affinity DataKi:  8.30nMAssay Description:Binding affinity at human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50173708(CHEMBL198298 | N,N-dimethyl-3-phenyl-3-(4-(trifluo...)
Affinity DataKi:  6.63E+3nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed