BDBM50173967 (2S,4S)-1-((R)-2-amino-3-((5-chlorobenzo[b]thiophen-3-yl)methylsulfonyl)-3-methylbutanoyl)-4-fluoropyrrolidine-2-carbonitrile::CHEMBL199379

SMILES CC(C)([C@H](N)C(=O)N1C[C@@H](F)C[C@H]1C#N)S(=O)(=O)Cc1csc2ccc(Cl)cc12

InChI Key InChIKey=GUBNROKMFNBDBZ-GRDNDAEWSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173967   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50173967((2S,4S)-1-((R)-2-amino-3-((5-chlorobenzo[b]thiophe...)
Affinity DataKi:  40nMAssay Description:Inhibitory activity against human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50173967((2S,4S)-1-((R)-2-amino-3-((5-chlorobenzo[b]thiophe...)
Affinity DataKi:  5.16E+3nMAssay Description:Inhibitory activity against recombinant sepraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50173967((2S,4S)-1-((R)-2-amino-3-((5-chlorobenzo[b]thiophe...)
Affinity DataKi: >2.24E+4nMAssay Description:Inhibitory activity against recombinant DPP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed