BDBM50173975 (2S,4S)-1-((R)-3-(2-methoxybenzylsulfonyl)-2-amino-3-methylbutanoyl)-4-fluoropyrrolidine-2-carbonitrile::CHEMBL369977

SMILES COc1ccccc1CS(=O)(=O)C(C)(C)[C@H](N)C(=O)N1C[C@@H](F)C[C@H]1C#N

InChI Key InChIKey=KMWQBQMYQFTSLO-OFQRWUPVSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173975   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50173975((2S,4S)-1-((R)-3-(2-methoxybenzylsulfonyl)-2-amino...)
Affinity DataKi:  309nMAssay Description:Inhibitory activity against human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50173975((2S,4S)-1-((R)-3-(2-methoxybenzylsulfonyl)-2-amino...)
Affinity DataKi:  1.24E+4nMAssay Description:Inhibitory activity against recombinant sepraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50173975((2S,4S)-1-((R)-3-(2-methoxybenzylsulfonyl)-2-amino...)
Affinity DataKi: >2.24E+4nMAssay Description:Inhibitory activity against recombinant DPP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed