BDBM50174379 1-{3-[3-(2-Chloro-4,5-difluoro-benzoyl)-ureido]-4-methoxy-phenyl}-3-methyl-urea::CHEMBL198392

SMILES CNC(=O)Nc1ccc(OC)c(NC(=O)NC(=O)c2cc(F)c(F)cc2Cl)c1

InChI Key InChIKey=ROJNYKZWTOHRNU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174379   

TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50174379(1-{3-[3-(2-Chloro-4,5-difluoro-benzoyl)-ureido]-4-...)
Affinity DataIC50:  52.5nMpH: 7.2Assay Description:Logarithmic inhibitory concentration against human liver glycogen phosphorylase enzyme by the addition of glucose-1-phosphate and incubated for 40 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50174379(1-{3-[3-(2-Chloro-4,5-difluoro-benzoyl)-ureido]-4-...)
Affinity DataIC50:  53nMpH: 7.2Assay Description:Inhibitory concentration against human liver glycogen phosphorylase enzyme by the addition of glucose-1-phosphate upon incubating for 40 min at 25 de...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed