BDBM50176116 (Z)-4-[1-(4-Fluoro-benzyl)-5-methoxy-1H-indol-3-yl]-2-hydroxy-4-oxo-but-2-enoic acid::CHEMBL196391

SMILES COc1ccc2n(Cc3ccc(F)cc3)cc(C(=O)CC(=O)C(O)=O)c2c1

InChI Key InChIKey=MONSDTWEJSHHJO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50176116   

TargetIntegrase(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50176116((Z)-4-[1-(4-Fluoro-benzyl)-5-methoxy-1H-indol-3-yl...)
Affinity DataIC50:  19nMAssay Description:In vitro concentration required to inhibit the overall HIV-1 integrase strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50176116((Z)-4-[1-(4-Fluoro-benzyl)-5-methoxy-1H-indol-3-yl...)
Affinity DataIC50:  4nMAssay Description:In vitro concentration required to inhibit the HIV-1 integrase strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50176116((Z)-4-[1-(4-Fluoro-benzyl)-5-methoxy-1H-indol-3-yl...)
Affinity DataIC50:  2.71E+3nMAssay Description:In vitro concentration required to inhibit the HIV-1 integrase 3' strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed