BDBM50176270 (S)-1-(1H-pyrrolo[3,2-h]isoquinolin-1-yl)propan-2-amine::CHEMBL201897

SMILES C[C@H](N)Cn1ccc2ccc3ccncc3c12

InChI Key InChIKey=WLQHTTMOCDZDRH-JTQLQIEISA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50176270   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Vernalis

Curated by ChEMBL
LigandPNGBDBM50176270((S)-1-(1H-pyrrolo[3,2-h]isoquinolin-1-yl)propan-2-...)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]5HT from human 5HT2CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Vernalis

Curated by ChEMBL
LigandPNGBDBM50176270((S)-1-(1H-pyrrolo[3,2-h]isoquinolin-1-yl)propan-2-...)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]5HT from human 5HT2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Vernalis

Curated by ChEMBL
LigandPNGBDBM50176270((S)-1-(1H-pyrrolo[3,2-h]isoquinolin-1-yl)propan-2-...)
Affinity DataKi:  230nMAssay Description:Displacement of [125I]DOI from human 5HT2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Vernalis

Curated by ChEMBL
LigandPNGBDBM50176270((S)-1-(1H-pyrrolo[3,2-h]isoquinolin-1-yl)propan-2-...)
Affinity DataEC50:  473nMAssay Description:Binding to human 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Vernalis

Curated by ChEMBL
LigandPNGBDBM50176270((S)-1-(1H-pyrrolo[3,2-h]isoquinolin-1-yl)propan-2-...)
Affinity DataEC50:  62nMAssay Description:Binding to human 5HT2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Vernalis

Curated by ChEMBL
LigandPNGBDBM50176270((S)-1-(1H-pyrrolo[3,2-h]isoquinolin-1-yl)propan-2-...)
Affinity DataEC50:  73nMAssay Description:Binding to human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed