BDBM50176440 1-(4-(4-(2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)butyl)-3,4-dihydro-1H-benzo[b]azepine-2,5-dione::A-706149::CHEMBL201232

SMILES CC(C)(C)c1nc(cc(n1)C(F)(F)F)N1CCN(CCCCN2c3ccccc3C(=O)CCC2=O)CC1

InChI Key InChIKey=FKHBHNWGBJHKGW-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50176440   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50176440(1-(4-(4-(2-tert-butyl-6-(trifluoromethyl)pyrimidin...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity to human cloned dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50176440(1-(4-(4-(2-tert-butyl-6-(trifluoromethyl)pyrimidin...)
Affinity DataKi:  246nMAssay Description:Binding affinity to human cloned dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50176440(1-(4-(4-(2-tert-butyl-6-(trifluoromethyl)pyrimidin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against dopamine D5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50176440(1-(4-(4-(2-tert-butyl-6-(trifluoromethyl)pyrimidin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against dopamine D1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed