BDBM50177153 CHEMBL3814576

SMILES COCCOc1nc(-c2ccc(Cl)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1

InChI Key InChIKey=NFOSIFORXQYVMS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50177153   

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50177153(CHEMBL3814576)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50177153(CHEMBL3814576)
Affinity DataIC50:  3.02E+3nMAssay Description:Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50177153(CHEMBL3814576)
Affinity DataIC50:  1.55E+3nMAssay Description:Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50177153(CHEMBL3814576)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed