BDBM50177354 2-(3-(4-(2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl)piperazin-1-yl)propylthio)pyrimidin-4-ol::A-437203::CHEMBL439338

SMILES CC(C)(C)c1nc(cc(n1)C(F)(F)F)N1CCN(CCCSc2nccc(=O)[nH]2)CC1

InChI Key InChIKey=KXVAICSRMHXLJN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50177354   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50177354(2-(3-(4-(2-tert-butyl-6-(trifluoromethyl)pyrimidin...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity to human cloned dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50177354(2-(3-(4-(2-tert-butyl-6-(trifluoromethyl)pyrimidin...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity to dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50177354(2-(3-(4-(2-tert-butyl-6-(trifluoromethyl)pyrimidin...)
Affinity DataKi:  351nMAssay Description:Binding affinity to human cloned dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed