BDBM501774 4[6-(4-aminopiperidin-1-yl)-5- oxo-4-[(1R)-1-phenylethyl]-4,5- dihydropyrazin-2-yl]benzonitrile::US11028066, Example 12

SMILES C[C@H](c1ccccc1)n1cc(nc(N2CCC(N)CC2)c1=O)-c1ccc(cc1)C#N

InChI Key InChIKey=LJAKKDNQISJZMX-QGZVFWFLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 501774   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM501774(4[6-(4-aminopiperidin-1-yl)-5- oxo-4-[(1R)-1-phen...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent