BDBM50177482 1,2,3,11-Tetrahydro-5,11-diaza-benzo[a]trindene-4,6-dione::4,5,6,7-tetrahydro-1Hcyclopenta[a]pyrrolo[3,4-c]carbazole-1,3(2H)-dione::CHEMBL204250

SMILES O=C1NC(=O)c2c1c1CCCc1c1[nH]c3ccccc3c21

InChI Key InChIKey=UYZYLAFMPDNCIK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50177482   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177482(1,2,3,11-Tetrahydro-5,11-diaza-benzo[a]trindene-4,...)
Affinity DataIC50:  36nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177482(1,2,3,11-Tetrahydro-5,11-diaza-benzo[a]trindene-4,...)
Affinity DataIC50:  36nMAssay Description:Inhibition of human recombinant PARP1 in U251MG cells by CometAssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177482(1,2,3,11-Tetrahydro-5,11-diaza-benzo[a]trindene-4,...)
Affinity DataIC50:  36nMAssay Description:Inhibition of recombinant human PARP1 by in vitro assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177482(1,2,3,11-Tetrahydro-5,11-diaza-benzo[a]trindene-4,...)
Affinity DataIC50:  36nMAssay Description:Inhibition of recombinant human PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed