BDBM50177542 1-(4-(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-yl)propoxy)benzyl)-4,4-difluoropiperidine::CHEMBL203696

SMILES FC1(F)CCN(Cc2ccc(OCCCN3CCC(Cc4cnc[nH]4)CC3)cc2)CC1

InChI Key InChIKey=XDGUQVBQTIPEEA-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50177542   

TargetHistamine H3 receptor(GUINEA PIG)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50177542(1-(4-(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-y...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50177542(1-(4-(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-y...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of CYP2D6 by human liver microsome assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed