BDBM50177593 (5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)-[2-chloro-4-(3-methyl-pyrazol-1-yl)-phenyl]-methanone::(5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10(11H)-yl)(2-chloro-4-(3-methyl-1H-pyrazol-1-yl)phenyl)methanone::CHEMBL363910::VNA-932::WAY-VNA-932
SMILES Cc1ccn(n1)-c1ccc(C(=O)N2Cc3cccn3Cc3ccccc23)c(Cl)c1
InChI Key InChIKey=JXKQHDZUZGKDGO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 22 hits for monomerid = 50177593
Affinity DataKi: 40nMAssay Description:Binding affinity to V2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]-AVP from human V2 receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]AVP from human vasopressin V2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 125nMAssay Description:Binding affinity to OTR receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 199nMAssay Description:Displacement of [3H]-AVP from human OXR receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 199nMAssay Description:Displacement of [3H]AVP from human oxytocin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 344nMAssay Description:Displacement of [3H]-AVP from human V1A receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 344nMAssay Description:Displacement of [3H]AVP from human vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 465nMAssay Description:Binding affinity to V1A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to V1B receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Antagonist activity at OXR receptor in rat uterusMore data for this Ligand-Target Pair
Affinity DataEC50: 0.700nMAssay Description:Agonist activity at V2 receptor (unknown origin) by cAMP accumulation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.66E+3nMAssay Description:Antagonist activity at V1A receptor (unknown origin) by cAMP accumulation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 465nMAssay Description:Activity at human vasopressin V1a receptor expressed in CHO cells by NFAT-luciferase gene reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 125nMAssay Description:Activity at human oxytocin receptor expressed in CHO cells by NFAT-luciferase gene reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 39.9nMAssay Description:Activity at human vasopressin V2 receptor expressed in CHO cells by NFAT-luciferase gene reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Displacement of [3H]AVP from human V2 receptor transfected in LV2 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.740nMAssay Description:Binding to human V2 receptor expressed in LV2 cells by cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 778nMAssay Description:Displacement of [3H]AVP from human V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 80.3nMAssay Description:Displacement of [3H]AVP from human vasopressin V2 receptor expressed in mouse LV2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 778nMAssay Description:Displacement of [3H]Manning ligand from human vasopressin V1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 353nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptor expressed in CHO cellsMore data for this Ligand-Target Pair