BDBM50177711 (5-oxo-5,11-dihydro-10-thia-dibenzo[a,d]cyclohepten-7-yl)-acetic acid::CHEMBL202156

SMILES OC(=O)Cc1ccc2SCc3ccccc3C(=O)c2c1

InChI Key InChIKey=URRFMRCFYIOQKV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50177711   

TargetDNA helicase IV(Escherichia coli (strain K12))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50177711((5-oxo-5,11-dihydro-10-thia-dibenzo[a,d]cyclohepte...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of ATPase activity of Helicase4 from Escherichia coli in presence of ATP (5x Km(ATP)) and dT25 (5x KDNA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA helicase IV(Escherichia coli (strain K12))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50177711((5-oxo-5,11-dihydro-10-thia-dibenzo[a,d]cyclohepte...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of ATPase activity of Tyr473Ala mutated Helicase4 in presence of ATP (5x Km(ATP)) and dT25 (5x KDNA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed