BDBM501782 4-{4-methyl-6-[4- (methylamino)piperidin-1-yl]-3- (4-methylphenyl)-5-oxo-4,5- dihydropyrazin-2-yl}benzonitrile::US11028066, Example 20
SMILES CNC1CCN(CC1)c1nc(-c2ccc(cc2)C#N)c(-c2ccc(C)cc2)n(C)c1=O
InChI Key InChIKey=JCGNLVXIPOIVDN-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 501782
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair