BDBM501783 4-[6-(4-amino-4-methylpiperidin- 1-yl)-4-methyl-3-(4- methylphenyl)-5-oxo-4,5- dihydropyrazin-2-yl]benzonitrile::US11028066, Example 21
SMILES Cc1ccc(cc1)-c1c(nc(N2CCC(C)(N)CC2)c(=O)n1C)-c1ccc(cc1)C#N
InChI Key InChIKey=RAADKMUWNJUHTA-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 501783
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair