BDBM501788 4-[6-(4-aminopiperidin-1-yl)-4- ethyl-3-(4-methylphenyl)-5-oxo- 4,5-dihydropyrazin-2- yl]benzonitrile::US11028066, Example 26
SMILES CCn1c(-c2ccc(C)cc2)c(nc(N2CCC(N)CC2)c1=O)-c1ccc(cc1)C#N
InChI Key InChIKey=UHRVPYGFWCIOGE-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 501788
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair