BDBM50178972 4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-2,3-dihydro-1H-indene-2-carboxylic acid::CHEMBL203828

SMILES CC(C)c1cc(Oc2c(Br)cc3CC(Cc3c2Br)C(O)=O)ccc1O

InChI Key InChIKey=MOWQUCJYYNNJGX-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50178972   

TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio

Curated by ChEMBL
LigandPNGBDBM50178972(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-2,3-d...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human TRalpha1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

Curated by ChEMBL
LigandPNGBDBM50178972(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-2,3-d...)
Affinity DataEC50:  4.30nMAssay Description:Efficacy against TRAF-beta-1 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio

Curated by ChEMBL
LigandPNGBDBM50178972(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-2,3-d...)
Affinity DataEC50:  4.10nMAssay Description:Efficacy against TRAF-alpha-1 reporter cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

Curated by ChEMBL
LigandPNGBDBM50178972(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-2,3-d...)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of human TRbeta1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed