BDBM50179134 (R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((4,4-dimethyl-2-oxooxazolidin-3-yl)methyl)piperidin-1-yl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL381501
SMILES CC1(C)COC(=O)N1CC1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1)C1CCCCC1
InChI Key InChIKey=YHYBBOPOIUAVHY-FIRIVFDPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50179134
Affinity DataIC50: 230nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 550nMAssay Description:Activity against human MC1BR by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 2.40nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Activity against human MC1BR by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 340nMAssay Description:Activity against human MC5R by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cellsMore data for this Ligand-Target Pair