BDBM50179497 CHEMBL3814182
SMILES Clc1ccc(Nc2ncnc3ccc(NC(=S)NCCN4CCOCC4)cc23)cc1Cl
InChI Key InChIKey=GUJCOZPKOPABIC-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50179497
Affinity DataIC50: 9.10nMAssay Description:Inhibition of recombinant human EGFR expressed in baculovirus by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 653nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) expressed in mouse BaF/3 cells assessed as cell growth inhibition after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 772nMAssay Description:Inhibition of wild type EGFR (unknown origin) expressed in mouse BaF/3 cells assessed as cell growth inhibition after 72 hrs by MTS assayMore data for this Ligand-Target Pair