BDBM50179512 CHEMBL3814211
SMILES NC(=O)Nc1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1
InChI Key InChIKey=HAQCJWCZBZBVHO-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50179512
Affinity DataIC50: 315nMAssay Description:Inhibition of wild type EGFR (unknown origin) expressed in mouse BaF/3 cells assessed as cell growth inhibition after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.854nMAssay Description:Inhibition of recombinant human EGFR expressed in baculovirus by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 401nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) expressed in mouse BaF/3 cells assessed as cell growth inhibition after 72 hrs by MTS assayMore data for this Ligand-Target Pair