BDBM50179819 2-(4-(4-(2-chloro-4-(4-fluorophenoxy)phenoxy)butoxy)phenoxy)-2-methylpropanoic acid::CHEMBL377508

SMILES CC(C)(Oc1ccc(OCCCCOc2ccc(Oc3ccc(F)cc3)cc2Cl)cc1)C(O)=O

InChI Key InChIKey=DDPMKDJRWHFNKY-UHFFFAOYSA-N

Data  1 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50179819   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179819(2-(4-(4-(2-chloro-4-(4-fluorophenoxy)phenoxy)butox...)
Affinity DataEC50:  7.69E+3nMAssay Description:Binding affinity to human PPAR gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179819(2-(4-(4-(2-chloro-4-(4-fluorophenoxy)phenoxy)butox...)
Affinity DataEC50:  66nMAssay Description:Binding affinity to human PPAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179819(2-(4-(4-(2-chloro-4-(4-fluorophenoxy)phenoxy)butox...)
Affinity DataIC50:  7.69E+3nMAssay Description:Displacement of radio-labeled full agonist from PPARgamma receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179819(2-(4-(4-(2-chloro-4-(4-fluorophenoxy)phenoxy)butox...)
Affinity DataEC50:  35nMAssay Description:Transactivation by human PPAR alpha in COS1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179819(2-(4-(4-(2-chloro-4-(4-fluorophenoxy)phenoxy)butox...)
Affinity DataEC50:  284nMAssay Description:Transactivation by human PPAR delta in COS1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179819(2-(4-(4-(2-chloro-4-(4-fluorophenoxy)phenoxy)butox...)
Affinity DataEC50:  545nMAssay Description:Binding affinity to human PPAR deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed