BDBM50179997 2-fluoro-3-(7-trifluoromethylimidazo[1,2-a]pyrimidin-3-yl)biphenyl-2-carbonitrile::CHEMBL199690
SMILES Fc1c(cccc1-c1ccccc1C#N)-c1cnc2nc(ccn12)C(F)(F)F
InChI Key InChIKey=GXKGSEUULCEOTM-UHFFFAOYSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50179997
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp Laboratory
Curated by ChEMBL
Merck Sharp Laboratory
Curated by ChEMBL
Affinity DataKi: 0.940nMAssay Description:Displacement of [3H]Ro-151788 from human recombinant GABAA alpha5 in combination with beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp Laboratory
Curated by ChEMBL
Merck Sharp Laboratory
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]Ro-151788 from human recombinant GABAA alpha3 in combination with beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp Laboratory
Curated by ChEMBL
Merck Sharp Laboratory
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]-Ro15-1788 from human recombinant GABAA alpha1 in combination with beta-3-gamma-2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair