BDBM50180302 8-(6-iodo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(3-isopropylamino-propyl)adenine::8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine::8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE::CHEMBL200102::US10336757, Compound PU-H71::US10676476, Example 9
SMILES CC(C)NCCCn1c(Sc2cc3OCOc3cc2I)nc2c(N)ncnc12
InChI Key InChIKey=SUPVGFZUWFMATN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50180302
TargetHeat shock protein 75 kDa, mitochondrial(Homo sapiens (Human))
Ulsan National Institutes of Science and Technology (Unist)
Curated by ChEMBL
Ulsan National Institutes of Science and Technology (Unist)
Curated by ChEMBL
Affinity DataIC50: 257nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant human N-terminal His6-tagged TRAP1 (60 to 561 residues) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Ulsan National Institutes of Science and Technology (Unist)
Curated by ChEMBL
Ulsan National Institutes of Science and Technology (Unist)
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant HSP90alpha (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein 75 kDa, mitochondrial(Homo sapiens (Human))
Ulsan National Institutes of Science and Technology (Unist)
Curated by ChEMBL
Ulsan National Institutes of Science and Technology (Unist)
Curated by ChEMBL
Affinity DataIC50: 675nMAssay Description:Inhibition of PU-H71-FITC binding to recombinant wild-type human TRAP1 expressed in Escherichia coli BL21 (DE3) measured after 2 hrs by fluorescence ...More data for this Ligand-Target Pair