BDBM50180545 2-(3,5-bis(trifluoromethyl)benzyloxy)-6-(2-methyl-2H-tetrazol-5-yl)-1-phenyl-8-aza-bicyclo[3.2.1]octane::CHEMBL380684

SMILES Cn1nnc(n1)C1CC2(NC1CCC2OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ccccc1

InChI Key InChIKey=YYYWTXUDIDHHTH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180545   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180545(2-(3,5-bis(trifluoromethyl)benzyloxy)-6-(2-methyl-...)
Affinity DataKi:  100nMAssay Description:Displacement of [35S]labelled MK499 from cloned hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180545(2-(3,5-bis(trifluoromethyl)benzyloxy)-6-(2-methyl-...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]labelled substance P from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed