BDBM50180548 2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-phenyl-6-(phenylsulfonyl)-8-aza-bicyclo[3.2.1]octane::CHEMBL381555

SMILES C[C@@H](OC1CCC2NC1(CC2S(=O)(=O)c1ccccc1)c1ccccc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=ZSJXCCAWETXSOR-HFQBRLDPSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180548   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180548(2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1...)
Affinity DataKi:  1.93E+3nMAssay Description:Displacement of [35S]labelled MK499 from cloned hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180548(2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [125I]labelled substance P from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed