BDBM50180551 2-(3,5-bis(trifluoromethyl)benzyloxy)-6-fluoro-6-(2-methyl-2H-tetrazol-5-yl)-1-phenyl-8-aza-bicyclo[3.2.1]octane::CHEMBL377091

SMILES Cn1nnc(n1)C1(F)CC2(NC1CCC2OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ccccc1

InChI Key InChIKey=UZFWWSXEIJUCEB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180551   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180551(2-(3,5-bis(trifluoromethyl)benzyloxy)-6-fluoro-6-(...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [35S]labelled MK499 from cloned hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180551(2-(3,5-bis(trifluoromethyl)benzyloxy)-6-fluoro-6-(...)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [125I]labelled substance P from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed