BDBM50180737 5,6-dimethyl-2-(pyridin-2-yl)-1H-benzo[d]imidazole::5,6-dimethyl-2-pyridin-2-yl-1H-benzoimidazole::CHEMBL371956::US8748618, LD-1-37

SMILES Cc1cc2nc([nH]c2cc1C)-c1ccccn1

InChI Key InChIKey=HXYMSNYVKWYLHV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50180737   

TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM50180737(5,6-dimethyl-2-(pyridin-2-yl)-1H-benzo[d]imidazole...)
Affinity DataIC50:  2.00E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM50180737(5,6-dimethyl-2-(pyridin-2-yl)-1H-benzo[d]imidazole...)
Affinity DataIC50:  2.84E+4nMAssay Description:Inhibition of human MetAP2 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Universit£T Heidelberg

Curated by ChEMBL
LigandPNGBDBM50180737(5,6-dimethyl-2-(pyridin-2-yl)-1H-benzo[d]imidazole...)
Affinity DataIC50:  3.26E+4nMAssay Description:Inhibition of human MetAP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine aminopeptidase(Escherichia coli (strain K12))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50180737(5,6-dimethyl-2-(pyridin-2-yl)-1H-benzo[d]imidazole...)
Affinity DataIC50:  2.43E+3nMAssay Description:Inhibition of Co2+ loaded MetAP expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed