BDBM501808 4-[6-(4-aminopiperidyl)-4-(3- hydroxypropyl)-3-(4- methylphenyl)-5-oxo(4- hydropyrazin-2-yl)]-2- fluorobenzenecarbonitrile::US11028066, Example 46
SMILES Cc1ccc(cc1)-c1c(nc(N2CCC(N)CC2)c(=O)n1CCCO)-c1ccc(C#N)c(F)c1
InChI Key InChIKey=YDOYSVOUCVUHTF-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 501808
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair