BDBM501812 4-[6-(4-amino-piperidin-1-yl)-3- (4-cyclopropyl-phenyl)-4-methyl- 5-oxo-4,5-dihydro-pyrazin-2-yl]- 2-fluoro-benzonitrile::US11028066, Example 50
SMILES Cn1c(-c2ccc(cc2)C2CC2)c(nc(N2CCC(N)CC2)c1=O)-c1ccc(C#N)c(F)c1
InChI Key InChIKey=RWFYTOFCBAGOBU-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 501812
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair