BDBM50181291 4-{3-[2-(4-biphenyl-3-yl-3-hydroxy-butyl)-5-oxo-pyrrolidin-1-yl]-propyl}-benzoic acid::CHEMBL208411

SMILES OC(CCC1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)Cc1cccc(c1)-c1ccccc1

InChI Key InChIKey=FBSYWZQEXIMEQD-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50181291   

TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181291(4-{3-[2-(4-biphenyl-3-yl-3-hydroxy-butyl)-5-oxo-py...)
Affinity DataIC50:  47nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181291(4-{3-[2-(4-biphenyl-3-yl-3-hydroxy-butyl)-5-oxo-py...)
Affinity DataEC50:  440nMAssay Description:Activity at rat EP4 transfected in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181291(4-{3-[2-(4-biphenyl-3-yl-3-hydroxy-butyl)-5-oxo-py...)
Affinity DataIC50: >3.20E+3nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed