BDBM50181317 3-(1H-benzo[d]imidazol-2-yl)-4-hydroxyquinolin-2(1H)-one::CHEMBL377345
SMILES Oc1c(-c2nc3ccccc3[nH]2)c(=O)[nH]c2ccccc12
InChI Key InChIKey=YXCWBNCDJZEBKY-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50181317
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of CHK1More data for this Ligand-Target Pair
Affinity DataIC50: 215nMAssay Description:Inhibitory activity against FGFR1More data for this Ligand-Target Pair
Affinity DataIC50: 114nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
Affinity DataIC50: 162nMAssay Description:Inhibitory activity against VEGFR1More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
Affinity DataIC50: 395nMAssay Description:Inhibitory activity against PDGFRbetaMore data for this Ligand-Target Pair