BDBM50181886 CHEMBL201669::N-(4'-dimethylaminomethyl-2'-methoxybiphenyl-4-carbonyl)-3-nitro-4-(2-phenylsulfanylethylamino)benzenesulfonamide

SMILES COc1cc(CN(C)C)ccc1-c1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(NCCSc2ccccc2)c(c1)[N+]([O-])=O

InChI Key InChIKey=ZOEQZRDHXXEEAC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50181886   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181886(CHEMBL201669 | N-(4'-dimethylaminomethyl-2'-methox...)
Affinity DataKi:  426nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181886(CHEMBL201669 | N-(4'-dimethylaminomethyl-2'-methox...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity to Bcl-XL in 1% human serum by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181886(CHEMBL201669 | N-(4'-dimethylaminomethyl-2'-methox...)
Affinity DataKi:  4.57E+3nMAssay Description:Binding affinity to Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed