BDBM50181929 1-cyclohexyl-2-(4-(dip-tolylmethoxy)phenyl)-1H-benzo[d]imidazole-5-carboxylic acid::CHEMBL203772

SMILES Cc1ccc(cc1)C(Oc1ccc(cc1)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O)c1ccc(C)cc1

InChI Key InChIKey=HJMQWRCMSAEVJK-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50181929   

TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50181929(1-cyclohexyl-2-(4-(dip-tolylmethoxy)phenyl)-1H-ben...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against HCV 1b NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50181929(1-cyclohexyl-2-(4-(dip-tolylmethoxy)phenyl)-1H-ben...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibitory activity against HCV 1a NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50181929(1-cyclohexyl-2-(4-(dip-tolylmethoxy)phenyl)-1H-ben...)
Affinity DataEC50:  3.70E+3nMAssay Description:Inhibition of HCV RNA replication in Huh5-2 cells after 48 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50181929(1-cyclohexyl-2-(4-(dip-tolylmethoxy)phenyl)-1H-ben...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50181929(1-cyclohexyl-2-(4-(dip-tolylmethoxy)phenyl)-1H-ben...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed