BDBM50182519 CHEMBL3818738::US9512121, 18

SMILES Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncc5NC(=O)COc5c4c3)n2c1

InChI Key InChIKey=PLFAGPHPVGUDTI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182519   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50182519(CHEMBL3818738 | US9512121, 18)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of c-Met (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Southeast University

Curated by ChEMBL
LigandPNGBDBM50182519(CHEMBL3818738 | US9512121, 18)
Affinity DataIC50:  9.30nMT: 2°CAssay Description:Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...More data for this Ligand-Target Pair
In DepthDetails US Patent