BDBM50182911 CHEMBL205870::N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-5-ethynylpyrimidin-4-amine

SMILES Fc1cccc(COc2ccc(Nc3ncncc3C#C)cc2Cl)c1

InChI Key InChIKey=KIUAMDPDOOLKMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182911   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50182911(CHEMBL205870 | N-(4-(3-fluorobenzyloxy)-3-chloroph...)
Affinity DataIC50:  85nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50182911(CHEMBL205870 | N-(4-(3-fluorobenzyloxy)-3-chloroph...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed