BDBM50182914 CHEMBL205652::N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)pyrimidin-4-amine

SMILES Fc1cccc(COc2ccc(Nc3ccncn3)cc2Cl)c1

InChI Key InChIKey=SSNRTALFAXFKNE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50182914   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50182914(CHEMBL205652 | N-(4-(3-fluorobenzyloxy)-3-chloroph...)
Affinity DataIC50:  320nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50182914(CHEMBL205652 | N-(4-(3-fluorobenzyloxy)-3-chloroph...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of HER2 by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50182914(CHEMBL205652 | N-(4-(3-fluorobenzyloxy)-3-chloroph...)
Affinity DataIC50:  920nMAssay Description:Inhibition of EGFR by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50182914(CHEMBL205652 | N-(4-(3-fluorobenzyloxy)-3-chloroph...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed