BDBM50182915 5-(2-(1H-pyrazol-3-yl)ethynyl)-N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)pyrimidin-4-amine::CHEMBL205284

SMILES Fc1cccc(COc2ccc(Nc3ncncc3C#Cc3ccn[nH]3)cc2Cl)c1

InChI Key InChIKey=IJCQFRPHONNGRV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182915   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50182915(5-(2-(1H-pyrazol-3-yl)ethynyl)-N-(4-(3-fluorobenzy...)
Affinity DataIC50:  42nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50182915(5-(2-(1H-pyrazol-3-yl)ethynyl)-N-(4-(3-fluorobenzy...)
Affinity DataIC50:  66nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed